There isn't enough space to really cover this. It is worth noting that most of these patients will not actually have MRSA or pseudomonas, so the basic principles of treating severe CAP still apply. When it comes to memorizing spectrum of activity for antibiotics, I first learn the rules for a class of antibiotics, then I focus on learning the exceptions to the rules. US Pharm. 2007;32(12)HS-10-HS-17. Antimicrobial stewardship is a marriage of infection control and judicious antimicrobial use whose primary goals are to optimize clinical outcomes and to minimize the emergence of antimicrobial resistance. 1 Effective antimicrobial stewardship requires the selection of specific antimicrobials for inpatient. By coverage. The following are lists of antibiotics for specific microbial coverage. MRSA. Antibiotics that cover methicillin-resistant Staphylococcus aureus (MRSA): DRUGS FOR URINARY TRACT INFECTIONS (UTI) Prepared by: Loren Regier Feb/05 1. Highlights Acute uncomplicated cystitis in otherwise healthy clinical consultations Gram-negative organisms Am J Health-Syst Pharm—Vol 68 Jan 15, 2011 119 clinical consultations Is double coverage of gram-negative INTRODUCTION. The fluoroquinolones have been a popular class of antibiotics for use in a variety of infections. Newer drugs in this class have been developed with a broader spectrum of activity including better coverage of gram-positive organisms and, for some fluoroquinolones, anaerobes. In June 2015 I did a post for MedEd101 termed “Bugs and Drugs Chart, Lessons Learned From the Front Lines.” About a year later I revisited the topic and since then the below information has been updated periodically. The newer fluoroquinolones have broad-spectrum bactericidal activity, excellent oral bioavailability, good tissue penetration and favorable safety and tolerability profiles. When doing empiric abx coverage, you may want to cover: Gram positives (Cocci & Rods) MRSA GNR (Gram-negative rods) Pseudomonas Anaerobes Antibiotics that Cover.